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KMID : 0359920110300040424
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Korean Journal of Nephrology
2011 Volume.30 No. 4 p.424 ~ p.428
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Acute Interstitial Nephritis during the First Course of Rifampin Administration in a Renal Transplant Patient
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Lee Hyun-Seung
Kim Hyun-Joo
Kang Mi-Seon
Park Seok-Ju
KIm Tae-Hee
Kang Sun-Woo
Kim Young-Hoon
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Abstract
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Tuberculosis is recognized as one of the most important complications in an organ transplant recipient. Rifampin has become a standard agent in the treatment of tuberculosis. While rifampin is well tolerated in most patients, adverse effects, including serious forms of toxicity, have been reported. Some of these adverse effects include liver toxicity and various immunologic reactions such as skin rashes, eosinophilia, and interstitial nephritis. We have experienced a case of acute interstitial nephritis during the first course of standard anti-tuberculous therapy in a renal transplant patient. We should not ignore other causes of interstitial nephritis in a renal transplant patient.
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KEYWORD
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Tuberculosis, Kidney transplantation, Rifampin, Interstitial nephritis
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